The Archbishop of Houston Galveston, Cardinal Daniel DiNardo, spent the two days at the border in South Texas visiting immigrant families and children.
He was joined by three bishops from across the country as well as clergy from the Diocese of Brownsville.
DiNardo described the experience as both beautiful and painful.
"We thought it was important to uplift the immigrants, be with them," DiNardo told FOX 26.
The group visited two detention centers in McAllen and Brownsville. The facility in Brownsville, Casa Padre, serves only teenage boys who are unaccompanied minors. The bishops celebrated mass with them.
"There was a sense of real seriousness, a stoic, somber kind of a look. It was very clear that they were well-cared for. The people who were working with them treated them well, but it’s also looking at children without their families," said Bishop Robert Brennan of the Diocese of Rockville Centre.
The delegation also visited the the Humanitarian Respite Center in McAllen to meet with families who were released by immigration officials.
When the bishops were asked how people who are both politically conservative and religious can reconcile their beliefs, they say the two can be lived together.
"When you have the opportunity to sit down with a family, liberal labels and conservative labels melt away," said Bishop Joseph Bambera of the Diocese of Scranton.
"I think people are worried about safety. I think we also need to be worried about the human voice, faces, and lives of those who come to us because they’re so fearful of where they live," DiNardo added.